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Spatial Analysis of Wildlife Tuberculosis Based on a Serologic Survey Using Dried Blood Spots, Portugal
- Source :
- Emerging Infectious Diseases, Vol 24, Iss 12, Pp 2169-2175 (2018), Emerging Infectious Diseases, Repositório Científico de Acesso Aberto de Portugal, Repositório Científico de Acesso Aberto de Portugal (RCAAP), instacron:RCAAP
- Publication Year :
- 2018
- Publisher :
- Centers for Disease Control and Prevention (CDC), 2018.
-
Abstract
- We investigated the spatial epidemiology of bovine tuberculosis (TB) in wildlife in a multihost system. We surveyed bovine TB in Portugal by serologic analysis of elutes of dried blood spots obtained from hunted wild boar. We modeled spatial disease risk by using areal generalized linear mixed models with conditional autoregressive priors. Antibodies against Mycobaterium bovis were detected in 2.4% (95% CI 1.5%-3.8%) of 678 wild boar in 2 geographic clusters, and the predicted risk fits well with independent reports of M. bovis culture. Results show that elutes are an almost perfect substitute for serum (Cohen unweighted κ = 0.818), indicating that serologic tests coupled with dried blood spots are an effective strategy for large-scale bovine TB surveys, using wild boar as sentinel species. Results also show that bovine TB is an emerging wildlife disease and stress the need to prevent further geographic spread and prevalence increase.<br />Plan Nacional (grant CGL2017-89866 from the Ministry of Economy and Competitiveness, Spain, and Fondo Europeo de Desarollo Regional) and Programa Operacional Regional do Norte (grant ON.2 O Novo Norte), Quadro de Referência Estratégico Nacional through the Fundo Europeu de Desenvolvimento Regional. N.S. was supported by PhD grant SFRH/BD/69390/2010 from Fundação para a Ciência e Tecnologia<br />info:eu-repo/semantics/publishedVersion
- Subjects :
- 0301 basic medicine
Wildlife tuberculosis
Epidemiology
red deer
Medicina Básica [Ciências Médicas]
lcsh:Medicine
serologic survey
Animal Diseases
Serology
Dried blood spots
wild animals
Prevalence
Public Health Surveillance
Geography, Medical
Socioeconomics
Dried blood
Mycobacterium bovis
biology
Spatial epidemiology
epidemiologic surveillance
Zoonoses, Portugal
3. Good health
Epidemiologic surveillance
Infectious Diseases
Geography
spatial epidemiology
Ciências Médicas::Medicina Básica
Tuberculosis and other mycobacteria
dried blood spots
Christian ministry
wild boar
Microbiology (medical)
Tuberculosis
Wildlife
Animals, Wild
Enzyme-Linked Immunosorbent Assay
Wild boar
Wild animals
lcsh:Infectious and parasitic diseases
Bovine tuberculosis
respiratory infections
03 medical and health sciences
biology.animal
medicine
Animals
Serologic Tests
lcsh:RC109-216
Spatial Analysis of Wildlife Tuberculosis Based on a Serologic Survey Using Dried Blood Spots, Portugal
Spatial Analysis
Science & Technology
Portugal
Bacteria
Research
lcsh:R
Respiratory infections
Serologic survey
medicine.disease
biology.organism_classification
zoonoses
tuberculosis and other mycobacteria
030104 developmental biology
cattle
Cattle
Dried Blood Spot Testing
Red deer
Subjects
Details
- ISSN :
- 10806059 and 10806040
- Volume :
- 24
- Database :
- OpenAIRE
- Journal :
- Emerging Infectious Diseases
- Accession number :
- edsair.doi.dedup.....e19460906e0b800ac24b8b1abd39c492