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Differential Diagnosis of Benign Spindle Cell Lesions

Authors :
Gaetano Magro
Source :
Surgical Pathology Clinics. 11:91-121
Publication Year :
2018
Publisher :
Elsevier BV, 2018.

Abstract

Spindle cell lesions of the breast cover a wide spectrum of diseases ranging from reactive tumor-like lesions to high-grade malignant tumors. The recognition of the benign spindle cell tumor-like lesions (nodular fasciitis; reactive spindle cell nodule after biopsy, inflammatory pseudotumor/inflammatory myofibroblastic tumor; fascicular variant of pseudoangiomatous stromal hyperplasia) and tumors (myofibroblastoma, benign fibroblastic spindle cell tumor, leiomyoma, schwannoma, spindle cell lipoma, solitary fibrous tumor, myxoma) is crucial to avoid confusion with morphologically similar but more aggressive bland-appearing spindle cell tumors, such as desmoid-type fibromatosis, low-grade (fibromatosis-like) spindle cell carcinoma, low-grade fibrosarcoma/myofibroblastic sarcoma and dermatofibrosarcoma protuberans.

Details

ISSN :
18759181
Volume :
11
Database :
OpenAIRE
Journal :
Surgical Pathology Clinics
Accession number :
edsair.doi.dedup.....e23573b143e65a6be27331f046972e85
Full Text :
https://doi.org/10.1016/j.path.2017.09.005