HLA association with HTLV-1/2 infection in different populations of Argentina

HLA class 1 alleles HLA-A*24,*26 and HLA-B*07,*61 were associated to susceptibility for HTLV-1 infection.While HLA-A*02 was associated to protection to HAM/TSP, HLA-B*07 was associated to susceptibility for disease. Alleles HLA-A*02 and HLA-B*27,*40,*48 were described in aboriginal populations of Russia genetically related to Andean aborigines. This study analyzed the association of HLA with susceptibility to HTLV-1 or -2 infections.