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The aortic mechanical properties in patients with the essential hypertension environmentally exposed to cigaret smoke
- Source :
- Inhalation toxicology. 27(13)
- Publication Year :
- 2015
-
Abstract
- The impairment of the aortic mechanical features constitutes the independent predictor of all-cause and cardiovascular mortality and morbidity.The purpose of the present research has been the determination of the influence of the environmental exposure to cigaret smoke on the aortic mechanical properties, namely, the stiffness and elasticity of aorta, in patients with essential hypertension.The research has covered 128 people with essential hypertension: 64 nonsmokers, declaring the environmental exposure to cigaret smoke (group A) and 64 nonsmokers declaring the lack of environmental exposure to cigaret smoke selected on the case to case basis (group B). Aortic mechanical properties have been evaluated on the basis of the parameters: aortic stiffness index (AoSI), aortic strain (AoS) and aortic distensibility (AoD).In group A, the average values of AoSI were significantly higher, and the average values of AoS and AoD significantly lower than in group B. It has been documented that the older age and environmental exposure to cigaret smoke form independent risk factors of increasing the aortic stiffness expressed by higher values of AoSI, whereas the older age, higher pulse pressure (PP) values and environmental exposure to cigaret smoke - independent risk factors of aortic elasticity reduction expressed for the age and "passive smoking" by lower values of AoS and AoD and for PP - lower values of AoD.In patients with essential hypertension, the environmental exposure to cigaret smoke seems to result in impairment of the aortic mechanical properties.
- Subjects :
- Male
medicine.medical_specialty
Health, Toxicology and Mutagenesis
Toxicology
Essential hypertension
Independent predictor
Vascular Stiffness
Internal medicine
medicine.artery
medicine
Humans
In patient
Aorta
Cardiovascular mortality
Smoke
business.industry
Environmental exposure
Environmental Exposure
Middle Aged
medicine.disease
Elasticity
Echocardiography
Hypertension
cardiovascular system
Cardiology
Aortic stiffness
Female
Tobacco Smoke Pollution
Essential Hypertension
business
Subjects
Details
- ISSN :
- 10917691
- Volume :
- 27
- Issue :
- 13
- Database :
- OpenAIRE
- Journal :
- Inhalation toxicology
- Accession number :
- edsair.doi.dedup.....e2b1c5579c8297e34a89e48b91d08d11