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A Randomized Trial of High-Dose Vitamin D2 in Relapsing-remitting Multiple Sclerosis

Authors :
P. Rieckmann
Luigi M.E. Grimaldi
Frederik Barkhof
H.H. Leitner
R. Hupperts
Joost Smolders
Myriam Schluep
Manolo Beelke
Joep Killestein
H. Burton
Trygve Holmøy
Radiology and nuclear medicine
Neurology
NCA - Multiple Sclerosis and Other Neuroinflammatory Diseases
Anesthesiology
Immunology
Source :
Leitner, H H, Grimaldi, L, Barkhof, F, Beelke, M, Burton, H, Holmoy, T, Hupperts, R, Killestein, J, Rieckmann, P, Schluep, M & Smolders, J 2012, ' A Randomized Trial of High-Dose Vitamin D2 in Relapsing-remitting Multiple Sclerosis ', Neurology, vol. 78, no. 11, pp. 840-841 . https://doi.org/10.1212/01.wnl.0000413180.13413.ce, Neurology, 78(11), 840-841. Lippincott Williams and Wilkins, Grimaldi, L, Barkhof, F, Beelke, M, Burton, J, Holmoy, T, Hupperts, R, Killestein, J, Rieckmann, P, Schluep, M, Smolders, J & Stenager, E 2012, ' A randomized trial of high-dose vitamin D2 in relapsing-remitting multiple sclerosis ', Neurology, vol. 78, no. 11, pp. 840-841 . https://doi.org/10.1212/01.wnl.0000413180.13413.ce, Neurology, 78(11). Lippincott Williams & Wilkins
Publication Year :
2012

Abstract

{#article-title-2} Stein et al.1 compared high- vs low-dose vitamin D2 treatment in MS without benefit in the high-dose treatment group. Sunlight exposure and reduced vitamin D3 levels independently contribute to MS risk. The effect of sunlight exposure is supported by decreased signs of actinic skin damage found in MS patients compared to controls.2 It is difficult to determine which of these 2 environmental factors is of primary importance as higher levels of sunlight exposure will enhance vitamin D levels. The incidence of …

Details

ISSN :
00283878
Database :
OpenAIRE
Journal :
Leitner, H H, Grimaldi, L, Barkhof, F, Beelke, M, Burton, H, Holmoy, T, Hupperts, R, Killestein, J, Rieckmann, P, Schluep, M & Smolders, J 2012, ' A Randomized Trial of High-Dose Vitamin D2 in Relapsing-remitting Multiple Sclerosis ', Neurology, vol. 78, no. 11, pp. 840-841 . https://doi.org/10.1212/01.wnl.0000413180.13413.ce, Neurology, 78(11), 840-841. Lippincott Williams and Wilkins, Grimaldi, L, Barkhof, F, Beelke, M, Burton, J, Holmoy, T, Hupperts, R, Killestein, J, Rieckmann, P, Schluep, M, Smolders, J & Stenager, E 2012, ' A randomized trial of high-dose vitamin D2 in relapsing-remitting multiple sclerosis ', Neurology, vol. 78, no. 11, pp. 840-841 . https://doi.org/10.1212/01.wnl.0000413180.13413.ce, Neurology, 78(11). Lippincott Williams & Wilkins
Accession number :
edsair.doi.dedup.....e2d4959dd2d74b24f489f479a302b130
Full Text :
https://doi.org/10.1212/01.wnl.0000413180.13413.ce