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Convulsive status epilepticus as the initial presentation of superwarfarin poisoning: a case report
- Source :
- Annals of Palliative Medicine. 10:7008-7012
- Publication Year :
- 2021
- Publisher :
- AME Publishing Company, 2021.
-
Abstract
- Bromadiolone, a widely-used rodent control drug, could act as a long-acting anticoagulant. Patients of bromadiolone poisoning often present with multiorgan hemorrhage. However, neurological symptoms of bromadiolone poisoning are seldom reported. We report a rare case with convulsive status epilepticus as the initial presentation of bromadiolone poisoning. A previously healthy 18-year-old man presented with persistent unconsciousness and repeated convulsive seizures. Magnetic resonance imaging revealed lesions in the corpus callosum. Laboratory test revealed the microscopic hematuria, prolonged prothrombin time, prolonged activated partial thromboplastin time and the presence of bromadiolone. The patient was diagnosed as the bromadiolone poisoning and treated with hemofiltration, vitamin K and prothrombin complex. Consciousness of the patient was regained and all neurological symptoms diminished after 7 days. Coagulopathy was totally corrected after 3 weeks, and a 2-month regimen of vitamin K supplementation was prescribed after discharge. Our case suggests that bromadiolone poisoning may involve the central nervous system. The atypical and initial symptoms of neurological disorders might lead to misdiagnosis of bromadiolone poisoning. Poisoning should be considered when acute neurological symptoms are combined with bleeding tendency. The vitamin K treatment is effective for both coagulopathy and central nervous system disorders in bromadiolone poisoning.
- Subjects :
- medicine.drug_class
medicine.medical_treatment
Bromadiolone
Hemorrhage
03 medical and health sciences
chemistry.chemical_compound
Status Epilepticus
0302 clinical medicine
Hemofiltration
Coagulopathy
Humans
Medicine
030212 general & internal medicine
Advanced and Specialized Nursing
medicine.diagnostic_test
business.industry
Convulsive status epilepticus
Anticoagulant
Unconsciousness
Anticoagulants
Rodenticides
4-Hydroxycoumarins
medicine.disease
Regimen
Anesthesiology and Pain Medicine
chemistry
Anesthesia
medicine.symptom
business
030217 neurology & neurosurgery
Partial thromboplastin time
Subjects
Details
- ISSN :
- 22245839 and 22245820
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- Annals of Palliative Medicine
- Accession number :
- edsair.doi.dedup.....e3367729d6c6881d81e058a267636798