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Sustained Response After Remdesivir and Convalescent Plasma Therapy in a B-Cell–Depleted Patient With Protracted Coronavirus Disease 2019 (COVID-19)
- Source :
- Clinical Infectious Diseases, Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
- Publication Year :
- 2020
- Publisher :
- Oxford University Press (OUP), 2020.
-
Abstract
- We provide detailed clinical, virological, and immunological data of a B-cell–depleted patient treated with obinutuzumab for follicular lymphoma with protracted coronavirus disease 2019 (COVID-19) and viremia. A sustained response was achieved after 2 courses of remdesivir and subsequent convalescent plasma therapy. Immunocompromised patients might require combined and prolonged antiviral treatment regimens.
- Subjects :
- 0301 basic medicine
obinutuzumab
Microbiology (medical)
Convalescent plasma
Coronavirus disease 2019 (COVID-19)
Follicular lymphoma
Viremia
remdesivir
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
follicular lymphoma
Obinutuzumab
Medicine
Humans
030212 general & internal medicine
Antiviral treatment
B cell
COVID-19 Serotherapy
Alanine
business.industry
SARS-CoV-2
Brief Report
Immunization, Passive
COVID-19
medicine.disease
Adenosine Monophosphate
COVID-19 Drug Treatment
030104 developmental biology
medicine.anatomical_structure
AcademicSubjects/MED00290
Infectious Diseases
chemistry
Sustained response
Immunology
convalescent plasma
business
Subjects
Details
- Language :
- English
- ISSN :
- 15376591 and 10584838
- Database :
- OpenAIRE
- Journal :
- Clinical Infectious Diseases
- Accession number :
- edsair.doi.dedup.....e36311d11a97f264df7cef6d7891faa1
- Full Text :
- https://doi.org/10.1093/cid/ciaa1637