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Towards the Enhancement of Essential Oil Components’ Antimicrobial Activity Using New Zein Protein-Gated Mesoporous Silica Microdevices
- Source :
- International Journal of Molecular Sciences, RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia, instname, International Journal of Molecular Sciences, Vol 22, Iss 3795, p 3795 (2021), INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF), Centro de Investigación Principe Felipe (CIPF), r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF), Volume 22, Issue 7
- Publication Year :
- 2021
- Publisher :
- MDPI, 2021.
-
Abstract
- [EN] The development of new food preservatives is essential to prevent foodborne outbreaks or food spoilage due to microbial growth, enzymatic activity or oxidation. Furthermore, new compounds that substitute the commonly used synthetic food preservatives are needed to stifle the rising problem of microbial resistance. In this scenario, we report herein, as far as we know, for the first time the use of the zein protein as a gating moiety and its application for the controlled release of essential oil components (EOCs). The design of microdevices consist of mesoporous silica particles loaded with essential oils components (thymol, carvacrol and cinnamaldehyde) and functionalized with the zein (prolamin) protein found in corn as a molecular gate. The zein protein grafted on the synthesized microdevices is degraded by the proteolytic action of bacterial enzymatic secretions with the consequent release of the loaded essential oil components efficiently inhibiting bacterial growth. The results allow us to conclude that the new microdevice presented here loaded with the essential oil component cinnamaldehyde improved the antimicrobial properties of the free compound by decreasing volatility and increasing local concentration.<br />This research was funded by the Government of Spain (projects RTI2018-100910-B-C41, RTI2018-101599-B-C22-AR and RTI2018-101599-B-C21-AR (MCUI/FEDER, EU)) and the Generalitat Valenciana (project PROMETEO 2018/024, grant numbers ACIF/2016/023 and APOSTD/2019/118).
- Subjects :
- Zein
Food spoilage
02 engineering and technology
Bacterial growth
E. coli
Molecular gate
01 natural sciences
Cinnamaldehyde
law.invention
lcsh:Chemistry
chemistry.chemical_compound
foodborne illnesses
law
Carvacrol
Food science
lcsh:QH301-705.5
Spectroscopy
Protease secretion
Food Preservatives
Corn
molecular gate
General Medicine
Silicon Dioxide
021001 nanoscience & nanotechnology
Controlled release
Anti-Bacterial Agents
Computer Science Applications
02.- Poner fin al hambre, conseguir la seguridad alimentaria y una mejor nutrición, y promover la agricultura sostenible
Food preservative
corn
protease secretion
0210 nano-technology
Porosity
essential oil components
TECNOLOGIA DE ALIMENTOS
mesoporous silica particles
Catalysis
Mesoporous silica particles
Article
Essential oil components
Inorganic Chemistry
zein
food preservative
QUIMICA ANALITICA
Oils, Volatile
Physical and Theoretical Chemistry
Molecular Biology
Essential oil
010405 organic chemistry
cinnamaldehyde
Organic Chemistry
Foodborne illnesses
QUIMICA INORGANICA
Mesoporous silica
0104 chemical sciences
coli
chemistry
lcsh:Biology (General)
lcsh:QD1-999
Subjects
Details
- Language :
- English
- ISSN :
- 14220067
- Volume :
- 22
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- International Journal of Molecular Sciences
- Accession number :
- edsair.doi.dedup.....e3aeebda86e1c320344c19953c28040e