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Supplementary Tables 1 through 7 from The Transcriptional Regulatory Network of Proneural Glioma Determines the Genetic Alterations Selected during Tumor Progression

Authors :
Peter Canoll
Andrea Califano
Jeffrey N. Bruce
Peter A. Sims
Steven Rosenfeld
Thomas Ludwig
Reena Shakya
Rachel Bruce
Samuel Bruce
Julia Sisti
Benjamin Kennedy
Jonathan Yun
Richard Leung
Craig Soderquist
Benjamin Amendolara
Liang Lei
Paolo Guarnieri
Mukesh Bansal
Adam M. Sonabend
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

XLSX - 1231K, Supplementary Table 1: List of genes deleted in 75 to 100% of the end-stage *PTEN tumors Supplementary Table 2: List of genes showing copy number gains in *PTEN end-stage and *PTEN/p53 mouse tumors. Supplementary Table 3: Genes that were deleted in 75-100% of *PTEN end-stage mouse tumors and at least 10% of human tumors within one of the four GBM subtypes mapped to their chromosomal location in the human genome. Supplementary Table 4: List of gene deletions that were specific for one of the four GBM subtypes. Supplementary Table 5: Correlation of proneural-specific genetic alterations and deletions identified by cross-species comparison. Supplementary Table 6: Spearman correlation for Verhaak gene sets show highest correlation for human proneural GBM subtype for 21 dpi *PTEN tumors, end-stage *PTEN tumors and *p53 end-stage tumors. Supplementary Table 7: MR identified from NB versus *PTEN 21 dpi and NB versus *PTEN end-stage mouse MARINas, and human NB versus proneural GBM (TCGA) MARINa.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....e3c2864195913075d68413f0508106cf