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Incidence and origin of Clostridium difficile in neonates
- Publication Year :
- 1984
-
Abstract
- The stools of 65 of 92 (71%) infants in a special care nursery yielded Clostridium difficile on culture. Ninety percent of stools collected after 6 to 35 days in the unit were positive, and 36% of these also contained toxin. When tested in vitro, 94% of the isolates produced toxin. Of 110 swabs collected from the environment of the unit, 9% were positive for C. difficile, but the stools of 12 nurses working on the unit were negative. Thirty-five vaginal swabs collected from mothers just before delivery were negative for C. difficile on culture, but 16 of their infants had C. difficile in their stools. It was concluded that there is a high carriage rate in the stools of neonates of C. difficile acquired progressively during the course of their stay in the special care unit. Infection is mainly from environmental sources rather than maternal transmission.
- Subjects :
- Microbiology (medical)
medicine.medical_specialty
Bacterial Toxins
Nurses
Microbiology
Feces
Clostridium
Bacterial Proteins
Pregnancy
Internal medicine
Intensive Care Units, Neonatal
medicine
Humans
biology
Incidence (epidemiology)
Infant, Newborn
Clostridium difficile
medicine.disease
biology.organism_classification
Carriage
medicine.anatomical_structure
Vaginal swabs
Vagina
Clostridium Infections
Female
Research Article
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....e3efc84ac6ab414faeec4a2ee1f421b4