Brown recluse spider bites

The brown recluse spider (Loxosceles reclusa), found in many areas of the United States, is capable of producing significant medical problems and potentially life-threatening systemic manifestations. This paper reviews the clinical presentation, diagnostic workup, pathophysiology, and management of the brown spider bite. Emphasis is placed on the potential for error in establishing this diagnosis. The need for a simplified management program is discussed along with current concepts on how to achieve this management program. Attention is also directed to the more serious complications.