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Liver transplantation as a definitive treatment for familial hypercholesterolemia: A series of 36 cases
- Source :
- Pediatric Transplantation. 19:605-611
- Publication Year :
- 2015
- Publisher :
- Wiley, 2015.
-
Abstract
- FH is a genetic disorder characterized by an increase in serum LDL and total cholesterol values. The afflicted patients are at increased risk of premature atherosclerosis and myocardial infarction. Different treatment modalities are present, including pharmacological agents and surgical procedures. The most effective method of therapy in refractive cases is liver transplantation. Herein, we report our experience on 36 cases of patients with FH undergoing liver transplantation in our center, the main referral center of liver transplantation in Iran. The clinical findings, hospital courses, post-operative complications, and patient follow-up are also described.
- Subjects :
- Adult
Male
medicine.medical_specialty
Adolescent
medicine.medical_treatment
Familial hypercholesterolemia
Liver transplantation
Hyperlipoproteinemia Type II
Young Adult
Postoperative Complications
Internal medicine
medicine
Humans
Myocardial infarction
Child
Retrospective Studies
Transplantation
business.industry
Genetic disorder
medicine.disease
Liver Transplantation
Surgery
Treatment Outcome
Increased risk
Premature atherosclerosis
Child, Preschool
Pediatrics, Perinatology and Child Health
Referral center
Female
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 13973142
- Volume :
- 19
- Database :
- OpenAIRE
- Journal :
- Pediatric Transplantation
- Accession number :
- edsair.doi.dedup.....e4d60793910ed33936ab2fc9efd5cc4a