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Darunavir/ritonavir monotherapy at a low dose (600/100 mg/day) in HIV-1-infected individuals with suppressed HIV viraemia

Authors :
Ruxandra Calin
Fabienne Caby
Gilles Peytavin
Marc-Antoine Valantin
Lambert Assoumou
Luminita Schneider
Sophie Seang
Minh Patrick Lê
Thuy Van Nguyen
A G Marcelin
Cathia Soulié
Roland Tubiana
Christine Katlama
Source :
The Journal of antimicrobial chemotherapy. 73(2)
Publication Year :
2017

Abstract

Background Darunavir/ritonavir is a potent PI with a high genetic barrier and pharmacological robustness favourably investigated as monotherapy. Whether darunavir could be dose reduced in the context of monotherapy deserves investigation. Methods Patients with HIV suppressed viraemia (plasma viral load

Details

ISSN :
14602091
Volume :
73
Issue :
2
Database :
OpenAIRE
Journal :
The Journal of antimicrobial chemotherapy
Accession number :
edsair.doi.dedup.....e568e8125602e9a26935fca0e1be5a3c