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Intravascular Lymphoma as an Uncommon Cause of Anasarca
- Source :
- European Journal of Case Reports in Internal Medicine, Vol 3, Iss 5 (2016), European Journal of Case Reports in Internal Medicine
- Publication Year :
- 2016
- Publisher :
- SMC MEDIA SRL, 2016.
-
Abstract
- Objectives To report a case of intravascular lymphoma (IVL) in a Caucasian patient who presented with anasarca as his sole clinical sign. Material and Methods A man presented with anasarca-type oedema and fatigue. After excluding heart failure, hepatic cirrhosis, nephrotic syndrome, hypothyroidism, AL-amyloidosis and adverse drug reaction which can all cause oedema, we turned our attention to capillary permeability disorders. Results Closer review of the bone marrow aspirate demonstrated haemophagocytic histiocytosis, while core, renal and duodenal biopsies showed a B-cell IVL. Conclusion The differential diagnosis of anasarca, a relatively common clinical sign, should include IVL although the diagnosis may still be challenging. LEARNING POINTS Anasarca-type oedema is an unusual initial presentation of intravascular lymphoma (IVL) and is normally attributed to capillary permeability disorders. Two clinical forms of IVL have been recognized: a Western form and an Asian variant which is characterized by haemophagocytosis. Patients of Caucasian origin who have the clinical features of the Asian variant of IVL make the diagnosis of this condition even more challenging.
- Subjects :
- Pathology
medicine.medical_specialty
Cirrhosis
Anasarca edema
intravascular lymphoma
lcsh:Medicine
Anasarca
03 medical and health sciences
0302 clinical medicine
Internal Medicine
medicine
haemophagocytosis
hemophagocytosis
business.industry
lcsh:R
Articles
Intravascular lymphoma
medicine.disease
Dermatology
Anasarca oedema
Histiocytosis
030220 oncology & carcinogenesis
Heart failure
030221 ophthalmology & optometry
medicine.symptom
Differential diagnosis
business
Nephrotic syndrome
Adverse drug reaction
Subjects
Details
- Language :
- English
- ISSN :
- 22842594
- Volume :
- 3
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- European Journal of Case Reports in Internal Medicine
- Accession number :
- edsair.doi.dedup.....e670095c2f6daca786d8721bcade4442