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Decontamination and Management of Contaminated Hair following a CBRN or HazMat Incident
- Source :
- Toxicological Sciences
- Publication Year :
- 2019
- Publisher :
- Oxford University Press (OUP), 2019.
-
Abstract
- This in vitro study evaluated the “triple protocol” of dry decontamination, the ladder pipe system (a method for gross decontamination), and technical decontamination for the decontamination of hair following chemical contamination. First, we assessed the efficacy of the 3 protocols, alone or in combination, on excised porcine skin and human hair contaminated with either methyl salicylate (MS), phorate (PHR), sodium fluoroacetate (SFA), or potassium cyanide (KCN). A second experiment investigated the residual hair contamination following decontamination with the triple protocol at different intervals postexposure. In a third experiment, hair decontaminated after exposure to MS or PHR was evaluated for off-gassing. Though skin decontamination was highly effective, a substantial proportion (20%–40%) of the lipophilic compounds (MS and PHR) remained within the hair. The more water-soluble contaminants (SFA and KCN) tended to form much smaller reservoirs within the hair. Interestingly, substantial off-gassing of MS, a medium volatility chemical, was detectable from triple-decontaminated hair up to 5 days postexposure. Overall, the decontamination strategies investigated were effective for the decontamination of skin, but less so for hair. These findings highlight the importance of contaminated hair serving as a source of potential secondary contamination by contact or inhalation. Therefore, consideration should be given to the removal of contaminated hair following exposure to toxic chemicals.
- Subjects :
- 0301 basic medicine
Post exposure
Potassium cyanide
Toxicology
01 natural sciences
secondary contamination
off-gassing
03 medical and health sciences
chemistry.chemical_compound
In vitro study
Porcine skin
Food science
skin decontamination
integumentary system
Inhalation
010401 analytical chemistry
Human decontamination
decontamination
Contamination
hair decontamination
0104 chemical sciences
030104 developmental biology
Regulatory Science, Risk Assessment and Decision Making
chemistry
Sodium fluoroacetate
mass casualty
Subjects
Details
- ISSN :
- 10960929 and 10966080
- Volume :
- 171
- Database :
- OpenAIRE
- Journal :
- Toxicological Sciences
- Accession number :
- edsair.doi.dedup.....e6c9200add66cdceb4daab44f11facf1
- Full Text :
- https://doi.org/10.1093/toxsci/kfz145