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Decontamination and Management of Contaminated Hair following a CBRN or HazMat Incident

Authors :
Philip Hughes
Joanne Larner
Nevine Amer
Elliot Thomas
Hazem Matar
Robert P. Chilcott
Mark Barrett
Andreia Tavares Pinhal
Source :
Toxicological Sciences
Publication Year :
2019
Publisher :
Oxford University Press (OUP), 2019.

Abstract

This in vitro study evaluated the “triple protocol” of dry decontamination, the ladder pipe system (a method for gross decontamination), and technical decontamination for the decontamination of hair following chemical contamination. First, we assessed the efficacy of the 3 protocols, alone or in combination, on excised porcine skin and human hair contaminated with either methyl salicylate (MS), phorate (PHR), sodium fluoroacetate (SFA), or potassium cyanide (KCN). A second experiment investigated the residual hair contamination following decontamination with the triple protocol at different intervals postexposure. In a third experiment, hair decontaminated after exposure to MS or PHR was evaluated for off-gassing. Though skin decontamination was highly effective, a substantial proportion (20%–40%) of the lipophilic compounds (MS and PHR) remained within the hair. The more water-soluble contaminants (SFA and KCN) tended to form much smaller reservoirs within the hair. Interestingly, substantial off-gassing of MS, a medium volatility chemical, was detectable from triple-decontaminated hair up to 5 days postexposure. Overall, the decontamination strategies investigated were effective for the decontamination of skin, but less so for hair. These findings highlight the importance of contaminated hair serving as a source of potential secondary contamination by contact or inhalation. Therefore, consideration should be given to the removal of contaminated hair following exposure to toxic chemicals.

Details

ISSN :
10960929 and 10966080
Volume :
171
Database :
OpenAIRE
Journal :
Toxicological Sciences
Accession number :
edsair.doi.dedup.....e6c9200add66cdceb4daab44f11facf1
Full Text :
https://doi.org/10.1093/toxsci/kfz145