Preferential Changes in Hepatosplanchnic Hemodynamics in Patients with Borderline Hypertension

To investigate changes in systemic and regional hemodynamics during the development of human hypertension, we simultaneously measured cardiac index (CI) by the indocyanine green (ICG) dye dilution method, hepatosplanchnic blood flow (HBF) by the ICG clearance method using a two-compartment model, and renal blood flow (RBF) by the p-aminohippurate clearance method in patients with borderline and essential hypertension. In patients with borderline hypertension (BH, n=27), HBF (435±15 ml/min/m2) and HBF/CI (16±1%) were significantly (p