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Determination of endocrine-disrupting chemicals in human milk by dispersive liquid-liquid microextraction
- Source :
- Bioanalysis. 8(17)
- Publication Year :
- 2016
-
Abstract
- Aim: Human populations are widely exposed to numerous so-called endocrine-disrupting chemicals, exogenous compounds able to interfere with the endocrine system. This exposure has been associated with several health disorders. New analytical procedures are needed for biomonitoring these xenobiotics in human matrices. A quick and inexpensive methodological procedure, based on sample treatment by dispersive liquid–liquid microextraction, is proposed for the determination of bisphenols, parabens and benzophenones in samples. Results: LOQs ranged from 0.4 to 0.7 ng ml-1 and RSDs from 4.3 to 14.8%. Conclusion: This methodology was satisfactorily applied in the simultaneous determination of a wide range of endocrine-disrupting chemicals in human milk samples and is suitable for application in biomonitoring studies.
- Subjects :
- Liquid Phase Microextraction
Clinical Biochemistry
Parabens
Food Contamination
010501 environmental sciences
Endocrine Disruptors
01 natural sciences
Analytical Chemistry
chemistry.chemical_compound
Benzophenones
Phenols
Limit of Detection
Tandem Mass Spectrometry
Biomonitoring
Liquid liquid
Humans
General Pharmacology, Toxicology and Pharmaceutics
Benzhydryl Compounds
Chromatography, High Pressure Liquid
0105 earth and related environmental sciences
Chromatography
Milk, Human
Chemistry
010401 analytical chemistry
General Medicine
0104 chemical sciences
Medical Laboratory Technology
Environmental chemistry
Xenobiotic
Subjects
Details
- ISSN :
- 17576199
- Volume :
- 8
- Issue :
- 17
- Database :
- OpenAIRE
- Journal :
- Bioanalysis
- Accession number :
- edsair.doi.dedup.....e7bb2a91b873362f2739d4117b7e308f