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Efficacy of Electro-acupuncture in Treatment of Functional Constipation: A Randomized Controlled Trial
- Source :
- Current Medical Science. 40:363-371
- Publication Year :
- 2020
- Publisher :
- Springer Science and Business Media LLC, 2020.
-
Abstract
- Functional constipation (FC) is a chronic disease that significantly affects the life quality of patients. Acupuncture has been used for the treatment of FC for many years, but its effectiveness has not been scientifically assessed. The present study aimed to evaluate the efficacy of electro-acupuncture (EA) in relieving the symptoms, mental states and quality of life (QOL) of FC patients. A total of 96 FC patients were randomly allocated into EA, mosapride & sham EA group (MS) and mosapride control group (MC). In the EA group, patients were treated with 16 sessions of needling at Quchi (LI11) and Shangjuxu (ST37) bilaterally, 5 times a week in the first 2 weeks, and 3 times a week in the last 2 weeks. In the MC group, patients were treated with 5 mg mosapride citrate three times a day for 4 weeks. In the MS group, patients underwent sham EA and the same mosapride citrate treatment as in the MC group. The primary outcome was the number of weekly spontaneous bowel movements (SBMs). The secondary outcomes included stool consistency, intensity of defecating difficulty, 36-Item Short-Form Health Survey (SF-36), Self-rating Anxiety Scale (SAS), Self-rating Depression Scale (SDS), and the validated Patient Assessment of Constipation-Quality of Life (PAC-QOL). The results showed that as compared with the baseline, EA significantly improved the weekly SBMs, stool consistency and intensity of defecating difficulty (P
- Subjects :
- Adult
Male
medicine.medical_specialty
Adolescent
Morpholines
Electro acupuncture
Biochemistry
Gastroenterology
Drug Administration Schedule
law.invention
Young Adult
Gastrointestinal Agents
Quality of life
Randomized controlled trial
law
Internal medicine
Genetics
medicine
Acupuncture
Humans
Dry needling
business.industry
Middle Aged
medicine.disease
Mosapride
Electroacupuncture
Treatment Outcome
Benzamides
Quality of Life
Defecation
Functional constipation
Female
business
Constipation
medicine.drug
Subjects
Details
- ISSN :
- 2523899X and 20965230
- Volume :
- 40
- Database :
- OpenAIRE
- Journal :
- Current Medical Science
- Accession number :
- edsair.doi.dedup.....e7d52742e8470b8771a9e6f6792e3d19