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Extracellular vesicles: An overview of biogenesis, function, and role in breast cancer
- Source :
- Tumor Biology, Vol 39 (2017)
- Publication Year :
- 2017
-
Abstract
- Extracellular vesicles have emerged as important mediators of intercellular communication and play an active role in cancer, including breast cancer. Despite limited studies, initial observations suggest that these vesicles are important in breast physiology and pathophysiology. We here, in brief, describe their potential use as future biomarkers and therapeutic agents in breast cancer. Extracellular vesicles in blood and breast fluid may have a great potential to detect and predict the presence of breast cancer, and extracellular vesicles modulation may emerge as a therapeutic approach in cancer therapy.
- Subjects :
- 0301 basic medicine
Breast Neoplasms
03 medical and health sciences
Therapeutic approach
Extracellular Vesicles
Breast cancer
Cell Line, Tumor
Biomarkers, Tumor
Medicine
Animals
Humans
skin and connective tissue diseases
RC254-282
business.industry
Vesicle
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Cancer
General Medicine
Genetic Therapy
medicine.disease
Microvesicles
Cell biology
030104 developmental biology
MCF-7 Cells
Female
business
Function (biology)
Biogenesis
Intracellular
Subjects
Details
- ISSN :
- 14230380
- Volume :
- 39
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
- Accession number :
- edsair.doi.dedup.....e82faa4e1bea28c823371849c8ead77e