Back to Search
Start Over
Sensory tricks in cervical dystonia correlate with enhanced brain activity during motor preparation
- Source :
- Parkinsonism Relat Disord
- Publication Year :
- 2020
-
Abstract
- Introduction Although sensory tricks are well known as the maneuvers that temporarily relieve dystonic symptoms in patients with cervical dystonia (CD), the underlying neurophysiological mechanisms remain unclear. We aimed to investigate brain potentials related to sensory tricks in patients with CD. Methods Thirteen patients with CD and 13 age-matched healthy volunteers participated. The experiment consisted of three conditions (moving the neck, moving an arm, and performing sensory tricks) presented in different blocks in random order in a contingent negative variation (CNV) paradigm. Warning and trigger stimuli (S1 and S2) were presented to the participants, who were instructed to prepare to perform the specific task for each condition after S1, and then to perform the task after S2. Early and late components of the CNV were measured. Results The late CNVs in patients with CD were significantly larger than those in healthy participants in Fz, FCz, Cz, and C3 electrodes. Only in patients with CD, the late CNVs were significantly greater for the ‘sensory tricks’ condition compared to the ‘move neck’ condition in Fz and C3 electrodes. Conclusion The late CNV is increased during sensory tricks in patients with CD, suggesting that sensory tricks may affect mechanisms related to the motor preparatory phase in the premotor and primary motor areas. Sensory tricks may normalize impaired motor preparation in dystonia, leading to improved dystonic symptoms.
- Subjects :
- 0301 basic medicine
Adult
medicine.medical_specialty
Brain activity and meditation
Sensory system
Contingent Negative Variation
Audiology
Motor Activity
Article
03 medical and health sciences
0302 clinical medicine
Medicine
Humans
In patient
Cervical dystonia
Preparatory phase
Torticollis
Aged
Dystonia
Cerebral Cortex
business.industry
Electroencephalography
Neurophysiology
Middle Aged
medicine.disease
Contingent negative variation
030104 developmental biology
Neurology
Touch Perception
Female
Neurology (clinical)
Geriatrics and Gerontology
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 18735126
- Volume :
- 84
- Database :
- OpenAIRE
- Journal :
- Parkinsonismrelated disorders
- Accession number :
- edsair.doi.dedup.....e86bb4fd19c4bb85feb0072c4932472c