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Bio-inspired dynamic biomolecule assembling for fine regulation of protein activity
- Source :
- Chemical Communications. 57:11205-11208
- Publication Year :
- 2021
- Publisher :
- Royal Society of Chemistry (RSC), 2021.
-
Abstract
- A versatile approach for the fine control of DNA-based hierarchical assembly via dual stimuli and two assembly strategies is developed. Moreover, with a reasonable design of functional thrombin aptamer structures on the formed DNA nanoassembly, it can achieve precise regulation of thrombin activity.
- Subjects :
- chemistry.chemical_classification
Biomolecule
Molecular Conformation
Thrombin
Metals and Alloys
Fibrinogen
DNA
General Chemistry
Aptamers, Nucleotide
Catalysis
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
chemistry.chemical_compound
Gene Expression Regulation
chemistry
Biomimetic Materials
Thrombin activity
Materials Chemistry
Ceramics and Composites
Biophysics
Protein activity
Protein Multimerization
Thrombin aptamer
Subjects
Details
- ISSN :
- 1364548X and 13597345
- Volume :
- 57
- Database :
- OpenAIRE
- Journal :
- Chemical Communications
- Accession number :
- edsair.doi.dedup.....e87e391f9fe0f8478f9d8edd77c448ba