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Cardiac and vascular complications in rheumatoid arthritis
- Source :
- Rheumatology, Vol 57, Iss 1, Pp 27-36 (2019), Reumatologia
- Publication Year :
- 2019
- Publisher :
- Termedia Publishing House, 2019.
-
Abstract
- Rheumatoid arthritis (RA) is an independent risk factor for the development of a variety of cardiovascular diseases, with a 1.5-factor increase in risk. This literature review aims to provide a global overview of the pathogenesis, effects of anti-rheumatoid treatment on cardiovascular risk, a description of the cardiovascular complications associated with RA, and current opinion on cardiovascular risk assessment and management in patients with RA. Author conducted a literature search in PubMed, Scopus, Web of Science and Embase regarding RA and associated cardiovascular complications. The mechanism of increased risk of cardiovascular disease in patients with RA is complex. There are specific genetic factors associated with both diseases, and traditional cardiovascular risk factors may be more prevalent in patients with RA. Most anti-rheumatic drugs decrease cardiovascular risk, and general recommendations focus on reduction of disease activity and strict management of cardiovascular risk as per the general population.
- Subjects :
- rheumatoid arthritis
medicine.medical_specialty
Immunology
Population
lcsh:Medicine
Disease
Pathogenesis
03 medical and health sciences
0302 clinical medicine
Rheumatology
Internal medicine
medicine
Immunology and Allergy
In patient
Risk factor
education
030203 arthritis & rheumatology
education.field_of_study
Review Paper
business.industry
Mechanism (biology)
cardiovascular
lcsh:R
medicine.disease
inflammation
Rheumatoid arthritis
atherosclerosis
Risk assessment
business
Subjects
Details
- Language :
- English
- ISSN :
- 20849834 and 00346233
- Volume :
- 57
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Rheumatology
- Accession number :
- edsair.doi.dedup.....e88bd6b7f009a4f6a3d9dcb9c3e96f7f