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Supplemental Figure 1 from MAP2K1 (MEK1) Mutations Define a Distinct Subset of Lung Adenocarcinoma Associated with Smoking
- Publication Year :
- 2023
- Publisher :
- American Association for Cancer Research (AACR), 2023.
-
Abstract
- Supplemental Figure 1. The F53L, Q56P, K57N and D67N mutants were sensitive to MEK inhibition when treated with the 1 μM of the MEK inhibitor Selumetinib (AZD6244). ERK activation decreased significantly after 30 minutes of treatment.
Details
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....e8aec0cb1b07448fba6c97ff8d58c6dd
- Full Text :
- https://doi.org/10.1158/1078-0432.22454591.v1