Saponin Rich Fractions (SRPs) from Soapwort Show Antioxidant and Hemolytic Activity

The present study established baseline data on hemolytic and antioxidant capacity of saponin rich fractions (SRFs) of Gypsophila arrostii, G. pilulifera and G. simonii (Caryophyllaceae) naturally found in Turkey. The antioxidant activity of the each SRF was carried out using 2 different methods: free-radical scavenging activity using 2,2-diphenyl-1-picryl hydrazyl (DPPH) and ABTS assay. Hemolytic activity of SRFs was tested using diluted sheep bloods and saline/distilled water as control groups. Also, total phenolic contents of each fraction were determined. Our results demonstrated that G. arrostii, G. pilulifera and G. simonii possessed strong antioxidant and the slight hemolytic activity when comparing the other saponin containing extracts. (C) 2013 The Authors. Published by Elsevier B.V.