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Sarcopenia and Vitamin D Deficiency in Patients with Crohn's Disease: Pathological Conditions That Should Be Linked Together
- Source :
- Nutrients, Vol 13, Iss 1378, p 1378 (2021), Nutrients
- Publication Year :
- 2021
-
Abstract
- Sarcopenia is a prevalent condition in patients with Crohn’s disease (CD), representing an independent predictor factor for the development of major postoperative complications. Thus, a proper assessment of the muscle strength, by using different validated tools, should be deemed an important step of the clinical management of these patients. Patients with CD are frequently malnourished, presenting a high prevalence of different macro- and micro-nutrient deficiencies, including that of vitamin D. The available published studies indicate that vitamin D is involved in the regulation of proliferation, differentiation, and regeneration of muscle cells. The relationship between vitamin D deficiency and sarcopenia has been extensively studied in other populations, with interesting evidence in regards to a potential role of vitamin D supplementation as a means to prevent and treat sarcopenia. The aim of this review was to find studies that linked together these pathological conditions.
- Subjects :
- Vitamin
Crohn’s disease
medicine.medical_specialty
Sarcopenia
Nutritional assess-ment
skeletal muscle function
Review
Disease
malnutrition
Gastroenterology
Inflammatory bowel disease
vitamin D deficiency
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Crohn Disease
inflammatory bowel disease
Internal medicine
Vitamin D and neurology
Prevalence
Medicine
Humans
TX341-641
030212 general & internal medicine
Vitamin D
Dietary Supplement
Crohn's disease
Nutrition and Dietetics
business.industry
Nutrition. Foods and food supply
medicine.disease
Vitamin D Deficiency
Malnutrition
chemistry
nutritional assessment
Dietary Supplements
030211 gastroenterology & hepatology
business
Human
Food Science
Subjects
Details
- ISSN :
- 20726643
- Volume :
- 13
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Nutrients
- Accession number :
- edsair.doi.dedup.....e8f0ee04265bb0d1bb17fb556fd2cb99