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'Benifuuki' Extract Reduces Serum Levels of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Ligands Containing Apolipoprotein B: A Double-Blind Placebo-Controlled Randomized Trial

Authors :
Toshiaki Hanafusa
Hiroyuki Sano
Hisashi Imbe
Masahiro Miyawaki
Jungo Terasaki
Akihisa Imagawa
Keiji Tanimoto
Hirofumi Tachibana
Reiko Fujisawa
Mari Maeda-Yamamoto
Source :
Nutrients, Vol 10, Iss 7, p 924 (2018), Nutrients, SC30201810090022, NARO成果DBa, OA, CC BY, Volume 10, Issue 7
Publication Year :
2018
Publisher :
MDPI AG, 2018.

Abstract

(1) Background: Arteriosclerosis is associated with high levels of low-density lipoprotein (LDL) cholesterol. O-methylated catechins in &ldquo<br />Benifuuki&rdquo<br />green tea are expected to reduce cholesterol levels, although there is limited research regarding this topic<br />(2) Methods: This trial evaluated 159 healthy volunteers who were randomized to receive ice cream containing a high-dose of &ldquo<br />extract including 676 mg of catechins (group H), a low-dose of &ldquo<br />extract including 322 mg of catechins (group L), or no &ldquo<br />extract (group C). Each group consumed ice cream (with or without extract) daily for 12 weeks, and their lipid-related parameters were compared<br />(3) Results: A significant reduction in the level of lectin-like oxidized LDL receptor-1 ligand containing ApoB (LAB) was detected in group H, compared to groups L and C. No significant differences between the three groups were detected in their levels of total cholesterol, triglycerides, and LDL cholesterol<br />(4) Conclusions: &ldquo<br />extract containing O-methylated catechins may help prevent arteriosclerosis.

Details

Language :
English
ISSN :
20726643
Volume :
10
Issue :
7
Database :
OpenAIRE
Journal :
Nutrients
Accession number :
edsair.doi.dedup.....e918f5a41c3d22e929cb8b9c972fd1d2
Full Text :
https://doi.org/10.3390/nu10070924