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Dehydroxylation of alcohols for nucleophilic substitution
- Source :
- Chemical communications (Cambridge, England). 54(51)
- Publication Year :
- 2018
-
Abstract
- The Ph3P/ICH2CH2I system-promoted dehydroxylative substitution of alcohols was achieved to construct C–O, C–N, C–S and C–X (X = Cl, Br, and I) bonds. Compared with the previous approaches such as the Appel reaction and Mitsunobu reaction, this protocol offers some practical advantages such as safe operation and a convenient amination process.
- Subjects :
- 010405 organic chemistry
Chemistry
Substitution (logic)
Metals and Alloys
General Chemistry
010402 general chemistry
01 natural sciences
Medicinal chemistry
Catalysis
0104 chemical sciences
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
Appel reaction
Safe operation
Materials Chemistry
Ceramics and Composites
Nucleophilic substitution
Mitsunobu reaction
Amination
Subjects
Details
- ISSN :
- 1364548X
- Volume :
- 54
- Issue :
- 51
- Database :
- OpenAIRE
- Journal :
- Chemical communications (Cambridge, England)
- Accession number :
- edsair.doi.dedup.....e92e708a97ea741f478803ac7c9b6e92