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National Trends in Antibiotic Use in Australian Residential Aged Care Facilities, 2005–2016
- Source :
- Clinical Infectious Diseases. 72:2167-2174
- Publication Year :
- 2020
- Publisher :
- Oxford University Press (OUP), 2020.
-
Abstract
- Background Understanding current patterns of antibiotic use in residential aged care facilities (RACFs) is essential to inform stewardship activities, but limited utilization data exist. This study examined changes in prevalence and consumption of antibiotics in Australian RACFs between 2005–2006 and 2015–2016. Methods This population-based, repeated cross-sectional analysis included all long-term permanent residents of Australian RACFs between July 2005 and June 2016 who were aged ≥ 65 years. The yearly prevalence rate of antibiotic use and number of defined daily doses (DDDs) of systemic antibiotics per 1000 resident-days were determined annually from linked pharmaceutical claims data. Trends were assessed using ordinary least squares regression. Results This study included 502 752 residents from 3218 RACFs, with 424.9 million resident-days analyzed. Antibiotics were dispensed on 5 608 126 occasions during the study period, of which 88% were for oral use. Cefalexin, amoxicillin-clavulanic acid, and trimethoprim were the most commonly dispensed antibiotics. The annual prevalence of antibiotic use increased from 63.8% (95% confidence interval [CI], 63.3%–64.4%) to 70.3% (95% CI, 69.9%–70.7%) between 2005–2006 and 2015–2016 (0.8% average annual increase, P Conclusions This nationwide study showed substantial increases in both prevalence of use and total consumption of antibiotics in Australian RACFs between 2005 and 2016. The increasingly widespread use of antibiotics in Australian RACFs is concerning and points to a need for enhanced efforts to optimize antibiotic use in this setting.
- Subjects :
- 0301 basic medicine
Microbiology (medical)
Drug Utilization
medicine.medical_specialty
030106 microbiology
nursing homes
03 medical and health sciences
0302 clinical medicine
Homes for the Aged
Humans
Medicine
030212 general & internal medicine
National trends
Aged care
Antibiotic use
Aged
business.industry
Australia
Anti-Bacterial Agents
Long-term care
Cross-Sectional Studies
Infectious Diseases
Family medicine
antimicrobial
long-term care
drug utilization
business
Nursing homes
Subjects
Details
- ISSN :
- 15376591 and 10584838
- Volume :
- 72
- Database :
- OpenAIRE
- Journal :
- Clinical Infectious Diseases
- Accession number :
- edsair.doi.dedup.....e9a2ca9e277878f78d814462321fc376