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The impact of particulate matter air pollution (PM2.5) on atherosclerosis in modernizing China: a report from the CATHAY study
- Source :
- International journal of epidemiology. 50(2)
- Publication Year :
- 2020
-
Abstract
- Background Air pollution has been associated with an increase in cardiovascular diseases incidence. To evaluate whether air pollution can accelerate atherogenic processes, we assessed the effects of air pollution on important surrogate markers of atherosclerosis [brachial flow-mediated dilation (FMD) and carotid intima-media thickness (IMT)]. Methods A total of 1656 Han Chinese (mean age 46.0 + 11.2 years; male 47%) in Hong Kong, Macau, Pun Yu, Yu County and the 3-Gorges Territories (Yangtze River) were studied between 1996 and 2007 [Chinese Atherosclerosis in the Aged and Young Project (the CATHAY Study)]. Cardiovascular risk profiles were evaluated. Particulate matter with an aerodynamic diameter Results Health parameters [age, gender, body mass index, waist : hip ratio (WHR) and glucose)] were similar in lowest and highest PM2.5 exposure tertiles, systolic and diastolic blood pressures and triglycerides were higher (P Conclusions Air pollution is strongly associated with markers of early atherosclerosis, suggesting a potential target for preventive intervention.
- Subjects :
- Adult
Male
medicine.medical_specialty
China
Waist
Epidemiology
Diastole
030204 cardiovascular system & hematology
Carotid Intima-Media Thickness
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Risk Factors
Internal medicine
Air Pollution
Medicine
Aerodynamic diameter
Humans
030212 general & internal medicine
Aged
business.industry
Cholesterol
General Medicine
Middle Aged
Atherosclerosis
Confidence interval
Blood pressure
chemistry
Cardiology
Yangtze river
Hong Kong
Particulate Matter
business
Body mass index
Subjects
Details
- ISSN :
- 14643685
- Volume :
- 50
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- International journal of epidemiology
- Accession number :
- edsair.doi.dedup.....e9d513b4366625085dd56d71f564ca7e