Cerebral amyloid angiopathy, leukoencephalopathy and dementia of acute onset. Clinicopathological study of a new case

Cerebral amyloid angiopathy (CAA) is a well-established cause of brain hemorrhage in the elderly. The association of CAA with other structural brain lesions is less well known. We report a 69 year old diabetic woman with dementia of acute onset Cranial CT and MRI showed diffuse leukoencephalopathy with predominant right parieto-occipital distribution. Pathological study demonstrated severe CAA. We review the association of CAA with dementia and leukoencephalopathy.