Supplementary Figures from Induction of Paracrine Signaling in Metastatic Melanoma Cells by PPARγ Agonist Rosiglitazone Activates Stromal Cells and Enhances Tumor Growth

Four supplementary figures showing - PPARg activation regulates pro-inflammatory cytokine expression in A375 melanoma cells - Impact of RGZ exposure on the expression of PPARg-target genes and of pro-inflammatory cytokines in a variety of cancer cell lines - Impact of direct exposure to RGZ or T0070907 on interleukin receptor expression, proliferation, cell cycle, apoptosis and senescence of A375 cells, and on human fibroblasts, endothelial cells and monocytes - Impact of the exposure to RGZ or to RGZ-conditioned media collected from different human melanoma cells on human endothelial cells, human fibroblasts, murine fibroblasts and murine endothelial cells