Back to Search Start Over

Prevalence and clinical characteristics of obstructive- and central-dominant sleep apnea in candidates of catheter ablation for atrial fibrillation in Japan

Authors :
Yoshiyasu Aizawa
Wakako Yamasawa
Seiji Takatsuki
Keiichi Fukuda
Takehiro Kimura
Kazuaki Nakajima
Akira Kunitomi
Shin Kashimura
Ryoma Fukuoka
Nobuhiro Nishiyama
Yoshinori Katsumata
Taishi Fujisawa
Koichi Fukunaga
Takahiko Nishiyama
Takashi Kohno
Source :
International journal of cardiology. 260
Publication Year :
2017

Abstract

Introduction We aimed to study the prevalence and types of sleep apnea (SA) as well as their clinical characteristics in atrial fibrillation (AF) ablation candidates in Japan. Methods Before catheter ablation, 197 consecutive AF patients (age: 60 ± 9 years, body mass index; 25.0 ± 3.0) were evaluated with portable polygraphy. We compared the clinical characteristics, according to the severity of SA as well as its types, as defined by the presence of obstruction and the mixed vs. central apnea indices. Results The mean apnea–hypopnea index (AHI) was 17.7 ± 11.9, with 135 AF patients having an AHI ≥10 (68.5%). Patients with an AHI ≥10 had a significantly higher body mass index, plasma brain natriuretic peptide (BNP) level, prevalence of hypertension, and larger left atrial size. Among patients with an AHI ≥10, the incidence of obstructive-dominant SA was 60.9% and that of central-dominant SA was 7.6%. The prevalence of hypertension was significantly higher in obstructive-dominant SA patients (obstructive vs. central: 48.3% vs. 20.0%, P = 0.038). The obstructive apnea index correlated with plasma BNP level and age, but the central and mixed apnea indices did not. Conclusions The prevalence of SA was common in AF ablation candidates, even without an obesity epidemic, and the SA type was predominantly obstructive. Portable polygraphy was useful for detecting undiagnosed SA patients in AF ablation candidates.

Details

ISSN :
18741754
Volume :
260
Database :
OpenAIRE
Journal :
International journal of cardiology
Accession number :
edsair.doi.dedup.....ea31d283e860e9da2e5db254f6c5bab3