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Prevalence and clinical characteristics of obstructive- and central-dominant sleep apnea in candidates of catheter ablation for atrial fibrillation in Japan
- Source :
- International journal of cardiology. 260
- Publication Year :
- 2017
-
Abstract
- Introduction We aimed to study the prevalence and types of sleep apnea (SA) as well as their clinical characteristics in atrial fibrillation (AF) ablation candidates in Japan. Methods Before catheter ablation, 197 consecutive AF patients (age: 60 ± 9 years, body mass index; 25.0 ± 3.0) were evaluated with portable polygraphy. We compared the clinical characteristics, according to the severity of SA as well as its types, as defined by the presence of obstruction and the mixed vs. central apnea indices. Results The mean apnea–hypopnea index (AHI) was 17.7 ± 11.9, with 135 AF patients having an AHI ≥10 (68.5%). Patients with an AHI ≥10 had a significantly higher body mass index, plasma brain natriuretic peptide (BNP) level, prevalence of hypertension, and larger left atrial size. Among patients with an AHI ≥10, the incidence of obstructive-dominant SA was 60.9% and that of central-dominant SA was 7.6%. The prevalence of hypertension was significantly higher in obstructive-dominant SA patients (obstructive vs. central: 48.3% vs. 20.0%, P = 0.038). The obstructive apnea index correlated with plasma BNP level and age, but the central and mixed apnea indices did not. Conclusions The prevalence of SA was common in AF ablation candidates, even without an obesity epidemic, and the SA type was predominantly obstructive. Portable polygraphy was useful for detecting undiagnosed SA patients in AF ablation candidates.
- Subjects :
- Male
medicine.medical_specialty
Central sleep apnea
medicine.medical_treatment
Central apnea
Catheter ablation
030204 cardiovascular system & hematology
03 medical and health sciences
0302 clinical medicine
Japan
Internal medicine
Atrial Fibrillation
Prevalence
Medicine
Humans
Aged
Sleep Apnea, Obstructive
business.industry
Apnea
Sleep apnea
Atrial fibrillation
Middle Aged
medicine.disease
Brain natriuretic peptide
Sleep Apnea, Central
respiratory tract diseases
Obstructive sleep apnea
Cross-Sectional Studies
Cardiology
Catheter Ablation
Female
medicine.symptom
Cardiology and Cardiovascular Medicine
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 18741754
- Volume :
- 260
- Database :
- OpenAIRE
- Journal :
- International journal of cardiology
- Accession number :
- edsair.doi.dedup.....ea31d283e860e9da2e5db254f6c5bab3