BRAF ‐mutated malignant melanoma with chondrosarcomatous differentiation in inguinal nodal metastasis

Authors :: Francesca Abbati
Francesca Sperandi
Barbara Melotti
Emi Dika
Annalisa Altimari
Barbara Corti
Abbati F.
Altimari A.
Corti B.
Dika E.
Sperandi F.
Melotti B.
Source :: Clinical Case Reports, Clinical Case Reports, Vol 9, Iss 4, Pp 2200-2204 (2021)
Publication Year :: 2021
Publisher :: Wiley, 2021.
Abstract: We report the case of a young woman who developed metastatic melanoma in the inguinal nodal region, which acquired chondrosarcomatous differentiation and preserved the BRAF mutation found in the primary tumor. The patient was treated with a BRAF/MEK inhibitor combination therapy (dabrafenib/trametinib), which was demonstrated to be effective and well‐tolerated.<br />BRAF‐mutated melanoma with chondrosarcomatoid differentiation and response to targeted therapy.

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