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Quantifying duration of proteinuria remission and association with clinical outcome in IgA nephropathy

Authors :
Canney, M.
Barbour, S. J.
Zheng, Y.
Coppo, R.
Zhang, H.
Liu, Z. -H.
Matsuzaki, K.
Suzuki, Y.
Katafuchi, R.
Reich, H. N.
Cattran, D.
Russo, M. L.
Troyanov, S.
Cook, H. T.
Roberts, I.
Tesar, V.
Maixnerova, D.
Lundberg, S.
Gesualdo, L.
Emma, F.
Fuiano, L.
Beltrame, G.
Rollino, C.
Amore, A.
Camilla, R.
Peruzzi, L.
Praga, M.
Feriozzi, S.
Polci, R.
Segoloni, G.
Colla, L.
Pani, A.
Piras, D.
Angioi, A.
Cancarini, G.
Ravera, S.
Durlik, M.
Moggia, E.
Ballarin, J.
Di Giulio, S.
Pugliese, F.
Serriello, I.
Caliskan, Y.
Sever, M.
Kilicaslan, I.
Locatelli, F.
Del Vecchio, L.
Wetzels, J. F. M.
Peters, H.
Berg, U.
Carvalho, F.
da Costa Ferreira, A. C.
Maggio, M.
Wiecek, A.
Ots-Rosenberg, M.
Magistroni, R.
Topaloglu, R.
Bilginer, Y.
D'Amico, M.
Stangou, M.
Giacchino, F.
Goumenos, D.
Kalliakmani, P.
Gerolymos, M.
Galesic, K.
Geddes, C.
Siamopoulos, K.
Balafa, O.
Galliani, M.
Stratta, P.
Quaglia, M.
Bergia, R.
Cravero, R.
Salvadori, M.
Cirami, L.
Fellstrom, B.
Kloster Smerud, H.
Ferrario, F.
Stellato, T.
Egido, J.
Martin, C.
Floege, J.
Eitner, F.
Lupo, A.
Bernich, P.
Mene, P.
Morosetti, M.
van Kooten, C.
Rabelink, T.
Reinders, M. E. J.
Boria Grinyo, J. M.
Cusinato, S.
Benozzi, L.
Savoldi, S.
Licata, C.
Mizerska-Wasiak, M.
Martina, G.
Messuerotti, A.
Dal Canton, A.
Esposito, C.
Migotto, C.
Triolo, G.
Mariano, F.
Pozzi, C.
Boero, R.
Bellur, S.
Mazzucco, G.
Giannakakis, C.
Honsova, E.
Sundelin, B.
Di Palma, A. M.
Gutierrez, E.
Asunis, A. M.
Barratt, J.
Tardanico, R.
Perkowska-Ptasinska, A.
Arce Terroba, J.
Fortunato, M.
Pantzaki, A.
Ozluk, Y.
Steenbergen, E.
Soderberg, M.
Riispere, Z.
Furci, L.
Orhan, D.
Kipgen, D.
Casartelli, D.
Galesic Ljubanovic, D.
Gakiopoulou, H.
Bertoni, E.
Cannata Ortiz, P.
Karkoszka, H.
Groene, H. J.
Stoppacciaro, A.
Bajema, I.
Bruijn, J.
Fulladosa Oliveras, X.
Maldyk, J.
Ioachim, E.
Bavbek, N.
Cook, T.
Alpers, C.
Feehally, J.
Berthoux, F.
Bonsib, S.
D'Agati, V.
D'Amico, G.
Emancipator, S.
Emmal, F.
Fervenza, F.
Florquin, S.
Fogo, A.
Groene, H.
Haas, M.
Hill, P.
Hogg, R.
Hsu, S.
Hunley, T.
Hladunewich
Jennette, C.
Joh, K.
Julian, B.
Kawamura, T.
Lai, F.
Leung, C.
Li, L.
Li, P.
Liu, Z.
Massat, A.
Mackinnon, B.
Mezzano, S.
Schena, F.
Tomino, Y.
Walker, P.
Wang, H.
Weening, J.
Yoshikawa, N.
Zeng, C. -H.
Shi, S.
Nogi, C.
Suzuki, H.
Koike, K.
Hirano, K.
Yokoo, T.
Hanai, M.
Fukami, K.
Takahashi, K.
Yuzawa, Y.
Niwa, M.
Yasuda, Y.
Maruyama, S.
Ichikawa, D.
Suzuki, T.
Shirai, S.
Fukuda, A.
Fujimoto, S.
Trimarchi, H.
Anesthesiology
Pathology
Graduate School
ACS - Heart failure & arrhythmias
ACS - Atherosclerosis & ischemic syndromes
Source :
Clinical journal of the American Society of Nephrology, 32(2). American Society of Nephrology, J Am Soc Nephrol, Journal of the American Society of Nephrology, 32, 436-447, Journal of the American Society of Nephrology, 32, 2, pp. 436-447, Journal of the American Society of Nephrology, 32(2), 436-447. American Society of Nephrology
Publication Year :
2021

Abstract

Contains fulltext : 232930.pdf (Publisher’s version ) (Closed access) BACKGROUND: On the basis of findings of observational studies and a meta-analysis, proteinuria reduction has been proposed as a surrogate outcome in IgA nephropathy. How long a reduction in proteinuria needs to be maintained to mitigate the long-term risk of disease progression is unknown. METHODS: In this retrospective multiethnic cohort of adult patients with IgA nephropathy, we defined proteinuria remission as a ≥25% reduction in proteinuria from the peak value after biopsy, and an absolute reduction in proteinuria to

Subjects

Subjects :
Male
Time Factors
glomerular disease
030232 urology & nephrology
030204 cardiovascular system & hematology
Gastroenterology
0302 clinical medicine
Outcome Assessment, Health Care
Clinical endpoint
Medicine
Clinical Epidemiology
Proteinuria
medicine.diagnostic_test
Remission Induction
Hazard ratio
IgA nephropathy
General Medicine
Middle Aged
end stage kidney disease
epidemiology and outcomes
proteinuria
renal function decline
renal pathology
3. Good health
Renal pathology
Nephrology
Disease Progression
Female
medicine.symptom
Glomerular Filtration Rate
Adult
medicine.medical_specialty
Nephropathy
03 medical and health sciences
Internal medicine
Biopsy
Humans
Proportional Hazards Models
Retrospective Studies
business.industry
Surrogate endpoint
Glomerulonephritis, IGA
medicine.disease
Confidence interval
Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11]
Kidney Failure, Chronic
Renal disorders Radboud Institute for Health Sciences [Radboudumc 11]
business

Details

Language :
English
ISSN :
10466673
Database :
OpenAIRE
Journal :
Clinical journal of the American Society of Nephrology, 32(2). American Society of Nephrology, J Am Soc Nephrol, Journal of the American Society of Nephrology, 32, 436-447, Journal of the American Society of Nephrology, 32, 2, pp. 436-447, Journal of the American Society of Nephrology, 32(2), 436-447. American Society of Nephrology
Accession number :
edsair.doi.dedup.....eb8a7d0c4ce49220be238bc583d4d245

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