Skin CD30+ T cells and circulating levels of soluble CD30 are increased in patients with graft versus host disease

Authors :: Marisa Benagiano
Mario Milco D'Elios
Sofia D’Elios
Simona Brancati
Elena Niccolai
Chiara Della Bella
Alessia Grassi
Nicola Pimpinelli
Amedeo Amedei
Alberto Bosi
Source :: Auto-Immunity Highlights
Publication Year :: 2013
Publisher :: Springer Science and Business Media LLC, 2013.
Abstract: Objective To determine serum soluble CD30 (sCD30) levels in patients with graft versus host disease (GVHD). Methods Serum soluble CD30 levels and IgE levels were assayed by a sensitive ELISA in 57 patients with bone marrow transplantation, and in 44 healthy controls. We analyzed the type of effector T cells in patients with GVHD. Results Serum levels of sCD30 and serum IgE levels were significantly higher (p values

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