Antibacterial evaluation silver of nanocomposite on Staphylococcus aureus and Escherichia coli

Background The treatment of bacterial diseases has become an increase public health problem, since the conventional antimicrobial substances lose their effectiveness due to the microbial resistance phenomenon [1]. Silver is a metal with potential antibacterial activity, and showed significant efficacy against several species of bacteria. The silver activity to prevent microbial growth is enhanced when the metal is found as nanoparticles [2]. Silver nanoparticles (NPAG) have their bacteriostatic and bactericidal activity based on their ability to kill or inhibit growth of bacteria. Pathogenic microorganisms, both gram positive and negative were sensitive to NPAG. The NPAG may be employed in conjunction with the biopolymers forming a nanocomposite that emerge as a promising therapeutic alternative. The xanthan gum is a biopolymer with interesting properties for food, cosmetic and pharmaceutical industries, acting as gelling and stabilizing [3]. The present study in focused on the evaluation of silver nanocomposite activity against gram positive and gram negative bacteria. The disk diffusion well technique was used to assess the efficiency of the silver nanocomposites against Staphylococcus aureus and Escherichia coli. The results indicated that the developed product has a broad spectrum of activity against the tested bacteria.