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Methemoglobinemia Following Monolinuron Ingestion: A Case Report in a Child
- Source :
- Pediatric emergency care. 34(3)
- Publication Year :
- 2016
-
Abstract
- Case We describe a case report of a 2-year-old boy presenting to the emergency department with cyanosis and agitation. There was no suggestive history of poisoning but parents reported the presence of an aquarium at the family dinner the night before, with an aquarium cleaner beside it. Physical examination at admission revealed central cyanosis without signs of respiratory distress. Oxygen saturation measured by pulse oximetry (SpO2) was at 80% in room air. Plasma level of methemoglobin was measured at 11.8%. After 6 hours, methemoglobin decreased spontaneously to 5% and pulse oximetry saturation reached 98% in room air. Consciousness, weakness, and behavior were concomitantly improved. Because of rapid and spontaneous improvement, no specific treatment such as methylene blue was administered. A mass spectrometry toxicological analysis was performed in a blood sample taken the day of admission. Screening procedure of pesticides based on liquid chromatography coupled with mass spectrometry identified monolinuron, a phenylurea herbicide. Conclusions We recommend considering acquired methemoglobinemia after ingestion of industrial products and drugs in children with cyanosis, mental status alteration, and without respiratory distress symptoms.
- Subjects :
- Male
Remission, Spontaneous
Physical examination
030204 cardiovascular system & hematology
Methemoglobinemia
Methemoglobin
Mass Spectrometry
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
medicine
Ingestion
Humans
Linuron
Oximetry
Pesticides
Cyanosis
medicine.diagnostic_test
Respiratory distress
business.industry
Oxygen Inhalation Therapy
General Medicine
Monolinuron
medicine.disease
030210 environmental & occupational health
3. Good health
Pulse oximetry
chemistry
Anesthesia
Child, Preschool
Pediatrics, Perinatology and Child Health
Emergency Medicine
Room air distribution
business
Chromatography, Liquid
Subjects
Details
- ISSN :
- 15351815
- Volume :
- 34
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Pediatric emergency care
- Accession number :
- edsair.doi.dedup.....ec8ca8a1d1dde95c31970f210590cbc4