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Triterpenoidal Saponins from the Barks of Zygophyllum fabago L
- Source :
- Chemical and Pharmaceutical Bulletin. 56:858-860
- Publication Year :
- 2008
- Publisher :
- Pharmaceutical Society of Japan, 2008.
-
Abstract
- Two new triterpenoid saponins, zygophylosides O (1) and P (2), have been isolated from the barks of Zygophyllum fabago L. Their structures were elucidated as 3beta-[(2-O-sulfo-beta-D-xylopyranosyl)oxy]urs-12-ene-27,28-dioic acid and 3beta-[(2-O-sulfo-beta-D-xylopyranosyl)oxy]urs-12-ene-27,28-dioic acid 28-beta-D-glucopyranoside, respectively, by spectral and chemical evidence. Compound 1 showed weaker Nitric Oxide (NO) inhibitory activity.
- Subjects :
- Spectrometry, Mass, Electrospray Ionization
Magnetic Resonance Spectroscopy
Spectrophotometry, Infrared
Stereochemistry
Zygophyllum
Molecular Conformation
Tetrazolium Salts
Nitric Oxide
Cell Line
Nitric oxide
Mice
chemistry.chemical_compound
Triterpenoid
Drug Discovery
Animals
Organic chemistry
Triterpenoid saponin
chemistry.chemical_classification
biology
Plant Extracts
Chemistry
Hydrolysis
Macrophages
General Chemistry
General Medicine
Saponins
biology.organism_classification
Triterpenes
Zygophyllum fabago
Thiazoles
Plant Bark
Subjects
Details
- ISSN :
- 13475223 and 00092363
- Volume :
- 56
- Database :
- OpenAIRE
- Journal :
- Chemical and Pharmaceutical Bulletin
- Accession number :
- edsair.doi.dedup.....ece2a6109a6b89525e69dde2ffcebc1a
- Full Text :
- https://doi.org/10.1248/cpb.56.858