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Effects of edaravone on reperfusion injury in patients with acute myocardial infarction

Authors :
Hidekazu Arai
Tomohiro Sakamoto
Michihiro Yoshimura
Satoru Hida
Hideki Shimomura
Yasuhiro Nagayoshi
Kenichi Tsujita
Masaya Fukuda
Jun Hokamaki
Yoshinori Nakamura
Hisao Ogawa
Hiroaki Kawano
Takuro Yamashita
Source :
The American Journal of Cardiology. 94:481-484
Publication Year :
2004
Publisher :
Elsevier BV, 2004.

Abstract

This clinical pilot study was a randomized, controlled, open-label study in 80 patients with acute myocardial infarction and was designed to examine the effects of a novel free radical scavenger, edaravone. Administration of edaravone before myocardial reperfusion was associated with smaller enzymatic infarcts and better clinical outcome.

Details

ISSN :
00029149
Volume :
94
Database :
OpenAIRE
Journal :
The American Journal of Cardiology
Accession number :
edsair.doi.dedup.....ed3c6e0a2a6a4bd5d1ae86a873fe6378
Full Text :
https://doi.org/10.1016/j.amjcard.2004.05.007