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Dimensions of Group-based Phylogenetic Mixtures
- Publication Year :
- 2017
- Publisher :
- arXiv, 2017.
-
Abstract
- In this paper we study group-based Markov models of evolution and their mixtures. In the algebreo-geometric setting, group-based phylogenetic tree models correspond to toric varieties, while their mixtures correspond to secant and join varieties. Determining properties of these secant and join varieties can aid both in model selection and establishing parameter identifiability. Here we explore the first natural geometric property of these varieties: their dimension. The expected projective dimension of the join variety of a set of varieties is one more than the sum of their dimensions. A join variety that realizes the expected dimension is nondefective. Nondefectiveness is not only interesting from a geometric point-of-view, but has been used to establish combinatorial identifiability for several classes of phylogenetic mixture models. In this paper, we focus on group-based models where the equivalence classes of identified parameters are orbits of a subgroup of the automorphism group of the group defining the model. In particular, we show that, for these group-based models, the variety corresponding to the mixture of $r$ trees with $n$ leaves is nondefective when $n \geq 2r+5$. We also give improved bounds for claw trees and give computational evidence that 2-tree and 3-tree mixtures are nondefective for small~$n$.<br />Comment: 24 pages, 4 figures
- Subjects :
- 0301 basic medicine
General Mathematics
Immunology
Dimension (graph theory)
Markov model
General Biochemistry, Genetics and Molecular Biology
Evolution, Molecular
Combinatorics
Mathematics - Algebraic Geometry
03 medical and health sciences
0302 clinical medicine
FOS: Mathematics
Abelian group
Quantitative Biology - Populations and Evolution
Algebraic Geometry (math.AG)
Phylogeny
General Environmental Science
Mathematics
Pharmacology
Models, Statistical
Models, Genetic
Group (mathematics)
General Neuroscience
Populations and Evolution (q-bio.PE)
Computational Biology
Mathematical Concepts
Join (topology)
Mixture model
Markov Chains
030104 developmental biology
Computational Theory and Mathematics
030220 oncology & carcinogenesis
FOS: Biological sciences
Identifiability
Variety (universal algebra)
General Agricultural and Biological Sciences
Subjects
Details
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....ed61c4afe3d5dbf227a8398f80b07f53
- Full Text :
- https://doi.org/10.48550/arxiv.1711.08686