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DiGeorge syndrome
- Source :
- Wiener Klinische Wochenschrift
- Publication Year :
- 2018
- Publisher :
- Springer Science and Business Media LLC, 2018.
-
Abstract
- Summary DiGeorge syndrome or 22q11.2 deletion syndrome is one of the most common genetic microdeletion syndromes in humans. In addition to physical manifestations, DiGeorge syndrome is associated with a high prevalence of psychiatric disorders, such as intellectual disability, schizophrenia and attention-deficit/hyperactivity disorder. Usually, the diagnosis of DiGeorge syndrome is made in early childhood. This article reports on the late diagnosis of a patient with panic disorder and comorbid major depression at the age of 51. Since genetic testing was not available before the 1990s, there might be many over 40-year-old patients, who remained undiagnosed. Psychiatric symptoms exhibit distinctive developmental trajectories and many of these exhibit an increase in incidence during adulthood. Hence, undiagnosed adult DiGeorge patients might present in psychiatric services. As in this case, a correct diagnosis of DiGeorge syndrome in adults may help to improve treatment and outcome.
- Subjects :
- Male
0301 basic medicine
medicine.medical_specialty
Short Report
030105 genetics & heredity
Marfan Syndrome
Craniosynostoses
03 medical and health sciences
0302 clinical medicine
22q11 Deletion Syndrome
DiGeorge syndrome
Intellectual disability
DiGeorge Syndrome
medicine
Humans
Psychiatry
Depression (differential diagnoses)
Psychiatric genetics
Genetic testing
22q11 deletion syndrome
Panic disorder
medicine.diagnostic_test
Depression
business.industry
General Medicine
Middle Aged
medicine.disease
Attention Deficit Disorder with Hyperactivity
Schizophrenia
business
030217 neurology & neurosurgery
Anxiety disorders
Subjects
Details
- ISSN :
- 16137671 and 00435325
- Volume :
- 130
- Database :
- OpenAIRE
- Journal :
- Wiener klinische Wochenschrift
- Accession number :
- edsair.doi.dedup.....ed64a90169cdd394c4ba987d6e055b8a