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Selected Natural Products in Neuroprotective Strategies for Alzheimer’s Disease—A Non-Systematic Review
- Source :
- International Journal of Molecular Sciences, Vol 23, Iss 1212, p 1212 (2022)
- Publication Year :
- 2022
- Publisher :
- MDPI AG, 2022.
-
Abstract
- Neurodegenerative disorders such as Alzheimer’s disease (AD) are distinguished by the irreversible degeneration of central nervous system function and structure. AD is characterized by several different neuropathologies—among others, it interferes with neuropsychiatrical controls and cognitive functions. This disease is the number one neurodegenerative disorder; however, its treatment options are few and, unfortunately, ineffective. In the new strategies devised for AD prevention and treatment, the application of plant-based natural products is especially popular due to lesser side effects associated with their taking. Moreover, their neuroprotective activities target different pathological mechanisms. The current review presents the anti-AD properties of several natural plant substances. The paper throws light on products under in vitro and in vivo trials and compiles information on their mechanism of actions. Knowledge of the properties of such plant compounds and their combinations will surely lead to discovering new potent medicines for the treatment of AD with lesser side effects than the currently available pharmacological proceedings.
- Subjects :
- Biological Products
QH301-705.5
Organic Chemistry
neurodegeneration
General Medicine
Catalysis
Computer Science Applications
Inorganic Chemistry
Chemistry
Neuroprotective Agents
Alzheimer Disease
Animals
Humans
Physical and Theoretical Chemistry
Biology (General)
Molecular Biology
Alzheimer’s disease
QD1-999
Spectroscopy
polyphenols
terpenes
secondary plant metabolites
dementia
Subjects
Details
- Language :
- English
- ISSN :
- 16616596 and 14220067
- Volume :
- 23
- Issue :
- 1212
- Database :
- OpenAIRE
- Journal :
- International Journal of Molecular Sciences
- Accession number :
- edsair.doi.dedup.....edb1bd222ffa79ad7acf232c4291826a