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Fitness Cost of SCC mec and Methicillin Resistance Levels in Staphylococcus aureus
- Source :
- Antimicrobial Agents and Chemotherapy. 48:2295-2297
- Publication Year :
- 2004
- Publisher :
- American Society for Microbiology, 2004.
-
Abstract
- Transformation of a type I SCC mec element into Staphylococcus aureus yielded highly oxacillin-resistant transformants with a reduced growth rate. Faster-growing variants could again be selected at the cost of reduced resistance levels, demonstrating an inverse correlation between oxacillin resistance levels and growth rate.
- Subjects :
- Staphylococcus aureus
DNA-Cytosine Methylases
Meticillin
Micrococcaceae
medicine.drug_class
Antibiotics
Colony Count, Microbial
610 Medicine & health
Penicillins
medicine.disease_cause
Microbiology
Plasmid
Mechanisms of Resistance
medicine
2736 Pharmacology (medical)
Pharmacology (medical)
Oxacillin
Antibacterial agent
Pharmacology
biology
10179 Institute of Medical Microbiology
SCCmec
2725 Infectious Diseases
biochemical phenomena, metabolism, and nutrition
biology.organism_classification
Electrophoresis, Gel, Pulsed-Field
Interspersed Repetitive Sequences
Transformation (genetics)
3004 Pharmacology
Infectious Diseases
Mutation
570 Life sciences
Methicillin Resistance
Transformation, Bacterial
Plasmids
medicine.drug
Subjects
Details
- ISSN :
- 10986596 and 00664804
- Volume :
- 48
- Database :
- OpenAIRE
- Journal :
- Antimicrobial Agents and Chemotherapy
- Accession number :
- edsair.doi.dedup.....ee10832837d737f420c67b29b646442b