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Successful palliative approach with high-intensity focused ultrasound in a patient with metastatic anaplastic pancreatic carcinoma: a case report
- Source :
- ecancermedicalscience
- Publication Year :
- 2016
-
Abstract
- We report a case of a 74-year-old man with a metastatic anaplastic pancreatic carcinoma (APC). After an early tumour progression on first-line chemotherapy with cisplatin and gemcitabine, even though it was badly tolerated, he was treated with a combination of systemic modified FOLFIRI and high-intensity focused ultrasound (HIFU) on the pancreatic mass. A tumour showing partial response with a clinical benefit was obtained. HIFU was preferred to radiotherapy because of its shorter course and minimal side effects, in order to improve the patient’s clinical conditions. The patient is currently on chemotherapy, asymptomatic with a good performance status. In referral centres, with specific expertise, HIFU could be safely and successfully combined with systemic chemotherapy for treatment of metastatic pancreatic carcinoma.
- Subjects :
- Oncology
Cancer Research
medicine.medical_specialty
abscopal effect
medicine.medical_treatment
Case Report
03 medical and health sciences
anaplastic pancreatic carcinoma
0302 clinical medicine
HIFU
palliative treatment
Internal medicine
Pancreatic mass
Medicine
Chemotherapy
Performance status
business.industry
Abscopal effect
medicine.disease
High-intensity focused ultrasound
Gemcitabine
Radiation therapy
030220 oncology & carcinogenesis
FOLFIRI
030211 gastroenterology & hepatology
business
medicine.drug
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- ecancermedicalscience
- Accession number :
- edsair.doi.dedup.....ee1dea9ae7aa358ad0225ea61b9164fa