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Henry Dale and the discovery of acetylcholine
- Source :
- Comptes Rendus Biologies. 329:419-425
- Publication Year :
- 2006
- Publisher :
- Elsevier BV, 2006.
-
Abstract
- In 1936 Sir Henry Dale of London and Professor Otto Loewi from Graz shared the Nobel Prize in Physiology or Medicine for their work on chemical neurotransmission. This paper uses much unpublished archival material to augment an examination of Dale's work, from his discovery of naturally occurring acetylcholine in 1913, through to evidence of its role as a neurotransmitter at autonomic ganglia, post-ganglionic parasympathetic nerve terminals and the neuromuscular junction.
- Subjects :
- Vagusstoff
Epinephrine
General Immunology and Microbiology
Philosophy
Neurophysiology
General Medicine
Parasympathetic nerve
History, 20th Century
Acetylcholine
humanities
General Biochemistry, Genetics and Molecular Biology
Neuromuscular junction
Nobel Prize
medicine.anatomical_structure
medicine
Animals
Humans
Chemical neurotransmission
General Agricultural and Biological Sciences
Classics
medicine.drug
Subjects
Details
- ISSN :
- 16310691
- Volume :
- 329
- Database :
- OpenAIRE
- Journal :
- Comptes Rendus Biologies
- Accession number :
- edsair.doi.dedup.....ee69a7b62c9dadefc5769c3d5dc276c1