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Endometrial cancer in a renal transplant recipient: A case report
- Source :
- Open Medicine, Open Medicine, Vol 15, Iss 1, Pp 981-985 (2020)
- Publication Year :
- 2020
- Publisher :
- Walter de Gruyter GmbH, 2020.
-
Abstract
- As the most effective treatment for end-stage renal diseases, renal transplantation can improve the quality of life of patients and prolong the survival time. However, during the prolonged survival time, malignancy has become one of the main causes of death of recipients, which vary geographically. Tumors in the digestive system and urothelial tumors have been highly reported in Asia. In general, the gynecological malignant tumors have been rarely reported, especially the endometrial carcinoma. Herein, a 63-year-old female renal transplant recipient diagnosed with endometrial carcinoma (15 years after transplantation) was reported. The patient had suffered irregular postmenopausal bleeding for a short time before hospitalization. She underwent abdominal hysterectomy, bilateral salpingo-oophorectomy, right pelvic lymphadenectomy, right para-aortic lymphadenectomy and omental excision. Postoperative pathology showed ovarian and pelvic lymph node metastasis and pathological stage IIIC. After six courses of chemotherapy with paclitaxel 270 mg + carboplatin 500 mg, the patient’s renal function was normal. During the third cycle of chemotherapy, the patient suffered a third-degree bone marrow suppression and returned to normal soon when treated with the recombinant human granulocyte stimulating factor. In conclusion, early screening of gynecologic tumors is important for female patients after renal transplantation, which has a positive significance for the prognosis improvement.
- Subjects :
- medicine.medical_specialty
medicine.medical_treatment
030232 urology & nephrology
endometrial carcinoma
030230 surgery
chemotherapy
Malignancy
03 medical and health sciences
0302 clinical medicine
Carcinoma
case report
Medicine
Stage IIIC
Chemotherapy
business.industry
Endometrial cancer
General Medicine
renal transplantation
medicine.disease
Surgery
Transplantation
Bone marrow suppression
Lymphadenectomy
business
Subjects
Details
- ISSN :
- 23915463
- Volume :
- 15
- Database :
- OpenAIRE
- Journal :
- Open Medicine
- Accession number :
- edsair.doi.dedup.....eedcc7f8834c2b44a3aaab11a6e3fafb