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Practical, Legal, and Ethical Issues in Expanded Access to Investigational Drugs

Authors :
Ameet Sarpatwari
Aaron S. Kesselheim
Jonathan J. Darrow
Jerry Avorn
Source :
New England Journal of Medicine. 372:279-286
Publication Year :
2015
Publisher :
Massachusetts Medical Society, 2015.

Abstract

The authors review the FDA policies and procedures that permit some patients with serious conditions to receive investigational drugs before formal product approval and examine the legal and ethical issues associated with expanded access.

Details

ISSN :
15334406 and 00284793
Volume :
372
Database :
OpenAIRE
Journal :
New England Journal of Medicine
Accession number :
edsair.doi.dedup.....ef5c4aef3a8b0211a37bc6e2dd8735dc