The effects of precurarization with a protective dose of d-tubocurarine in the conscious patient

Precurarization with a protective dose of d-tubocurarine, 6 mg in the adult male, 4 mg in the female, was achieved in a series of 100 patients three minutes before the induction of anaesthesia. This procedure was well tolerated on both psychological and physiological bases. The patients displayed no modification of their respiratory mechanics and could exhibit normal coordinated movements of their hands, legs and head. Slight diplopia and a sensation of drowsiness occurred frequently.