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Does Older Age have an Impact on Rituximab Efficacy and Safety? Results from the NOR-DMARD Register
- Source :
- Drugs & Aging. 37:617-626
- Publication Year :
- 2020
- Publisher :
- Springer Science and Business Media LLC, 2020.
-
Abstract
- The objective of this study was to compare the efficacy and safety of rituximab in older vs younger patients with rheumatoid arthritis. Data on 367 patients with rheumatoid arthritis treated with rituximab in the Norwegian Disease-Modifying Antirheumatic Drug (NOR-DMARD) register were analysed, comparing patients aged ≥ 65 years (n = 91) with patients aged
- Subjects :
- Adult
Male
musculoskeletal diseases
Drug
medicine.medical_specialty
Drug-Related Side Effects and Adverse Reactions
Immunosenescence
media_common.quotation_subject
Severity of Illness Index
Arthritis, Rheumatoid
03 medical and health sciences
0302 clinical medicine
Pharmacotherapy
Internal medicine
medicine
Humans
Pharmacology (medical)
Registries
030212 general & internal medicine
Adverse effect
Aged
media_common
medicine.diagnostic_test
Norway
business.industry
Confounding
Hazard ratio
Age Factors
Middle Aged
medicine.disease
Treatment Outcome
Antirheumatic Agents
Erythrocyte sedimentation rate
Rheumatoid arthritis
Female
Rituximab
Geriatrics and Gerontology
business
030217 neurology & neurosurgery
medicine.drug
Subjects
Details
- ISSN :
- 11791969 and 1170229X
- Volume :
- 37
- Database :
- OpenAIRE
- Journal :
- Drugs & Aging
- Accession number :
- edsair.doi.dedup.....efed3b0ad0b25e1b909dcc7dd46f2571