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Intrathoracic tumor of the chest wall: A case of Castleman’s disease mimicking myositis of the lower extremities
Intrathoracic tumor of the chest wall: A case of Castleman’s disease mimicking myositis of the lower extremities
- Source :
- General Thoracic and Cardiovascular Surgery. 65:664-666
- Publication Year :
- 2017
- Publisher :
- Springer Science and Business Media LLC, 2017.
-
Abstract
- Castleman's disease refers to a group of uncommon lymphoproliferative disorders which exhibit common lymph-node histological features. A 72-year-old male patient presented with signs of lower limb myositis. Detailed work-up focused initially on evaluating hematological malignancies, the presence of a solid tumor, autoimmune diseases and degenerative disorders of the peripheral nerves. Finally, a PET-CT scan was performed to exclude paraneoplastic manifestations of a primary tumor, revealing however a tumor of the thoracic wall. The definite histological diagnosis confirmed the presence of unicentric Castleman's disease of the chest wall. The manifestations of the present case suggest that a systemic inflammation might occur in the unicentric form of the disease possibly due to cytokine hypersecretion. The unicentric manifestation of the disease should be well distinguished from the multicentric appearance. Unicentric disease is a surgical condition and warrants a follow-up based on the systemic inflammation that might occur.
- Subjects :
- Male
Pulmonary and Respiratory Medicine
Pathology
medicine.medical_specialty
Degenerative Disorder
Biopsy
Lymphoproliferative disorders
Disease
Systemic inflammation
030218 nuclear medicine & medical imaging
Diagnosis, Differential
03 medical and health sciences
0302 clinical medicine
Surgical oncology
Positron Emission Tomography Computed Tomography
medicine
Humans
Thoracic Wall
Myositis
Aged
business.industry
Castleman Disease
General Medicine
Thoracic Neoplasms
medicine.disease
Primary tumor
medicine.anatomical_structure
Lower Extremity
030220 oncology & carcinogenesis
Surgery
medicine.symptom
Cardiology and Cardiovascular Medicine
business
Thoracic wall
Subjects
Details
- ISSN :
- 18636713 and 18636705
- Volume :
- 65
- Database :
- OpenAIRE
- Journal :
- General Thoracic and Cardiovascular Surgery
- Accession number :
- edsair.doi.dedup.....f003722266d8db629c2c1e2e8b54c459
- Full Text :
- https://doi.org/10.1007/s11748-016-0743-z