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Intrathoracic tumor of the chest wall: A case of Castleman’s disease mimicking myositis of the lower extremities

Intrathoracic tumor of the chest wall: A case of Castleman’s disease mimicking myositis of the lower extremities

Authors :
Athanasios Tampakis
Thomas Daikeler
Didier Lardinois
Ekaterini Christina Tampaki
Source :
General Thoracic and Cardiovascular Surgery. 65:664-666
Publication Year :
2017
Publisher :
Springer Science and Business Media LLC, 2017.

Abstract

Castleman's disease refers to a group of uncommon lymphoproliferative disorders which exhibit common lymph-node histological features. A 72-year-old male patient presented with signs of lower limb myositis. Detailed work-up focused initially on evaluating hematological malignancies, the presence of a solid tumor, autoimmune diseases and degenerative disorders of the peripheral nerves. Finally, a PET-CT scan was performed to exclude paraneoplastic manifestations of a primary tumor, revealing however a tumor of the thoracic wall. The definite histological diagnosis confirmed the presence of unicentric Castleman's disease of the chest wall. The manifestations of the present case suggest that a systemic inflammation might occur in the unicentric form of the disease possibly due to cytokine hypersecretion. The unicentric manifestation of the disease should be well distinguished from the multicentric appearance. Unicentric disease is a surgical condition and warrants a follow-up based on the systemic inflammation that might occur.

Details

ISSN :
18636713 and 18636705
Volume :
65
Database :
OpenAIRE
Journal :
General Thoracic and Cardiovascular Surgery
Accession number :
edsair.doi.dedup.....f003722266d8db629c2c1e2e8b54c459
Full Text :
https://doi.org/10.1007/s11748-016-0743-z